Facilities relevant to CM1306 Members

Instrumentation and large Research Facilities

Instruct-ERIC 

Instruct provides peer-reviewed access to research infrastructure (large facilities and lab-based) for structural biology aross Europe, as well as workshops and training. The website provides information on upcoming calls.

European Synchrotron Radiation Facility

3rd generation synchrotron source based in Grenoble, France. Currently undergoing upgrade to a diffraction  limited ring, open again for users in Sep 2020. Includes a number of specific endstations relevant to the Action

ID09 – time-resolved Laue beamline for SAXS/WAXS, diffraction and spectroscopy

Structural Biology Group beamlines – for SAXS and diffraction

Cryobench  – for optical and Raman spectroscopy combined with X-ray diffaraction

Cryo-EM Facility – facilities for single particle reconstruction and tomography

EMBL-Hamburg beamlines at PETRA III 

set of beamlines at the 3rd generation synchrotron source PETRA III operated by the European Molecular Biology Laboratory.

P12 – SAXS beamline with the possibility of time-resolved experiments

P13 – MX beamline

P14 – Microfocus MX beamline

P14-2 T-REXX – dedicated time-resolved serial crystallography beamline operated by EMBL in collaboration with Universität Hamburg.

Sample Preparation Characterisation Facility  – User core facility for sample optimisation and characterisation

European XFEL

state-of-the-art Free Electron Laser facility, ideal for ultrafast time-resolved experiments.

SPB/SFX – endstation for single particle and serial crystallographic diffraction experiments

FXE – endstation for pump-probe X-ray spectroscopy and scattering

Diamond Light Source

3rd generation synchrotron source near Oxford in the UK that operates a suite of macromolecular crystallography, imaging, scattering and spectroscopy beamlines relevant to CM1306 members. Diamond also operates eBIC, a cryo-EM facility.

Synchrotron SOLEIL

French national synchrotron source located near Paris. Operates two beamlines for macromolecular crystallography (PROXIMA 1 and 2A), as well as scattering.

ALBA

Spanish national synchrotron source located in Barcelona. Operates beamlines for macromolecular crystallography, scattering and imaging.

BESSY II

3rg generation synchrotron source with a strong focus on soft X-rays. Operates beamlines for macromolecular crystallography as well as a wide range of spectroscopy beamlines.

Swiss Light Source

Swiss national synchrotron that operates 3 beamlines for macromolecular crystallography, scattering and imaging. Also available is the SpectroLab for complementary spectroscopic/diffraction experiments.

SwissFEL

Swiss X-ray free electron laser source, very recently opened to users with facilites for serial femtosecond crystallography.

MAXIV

Swedish national synchrotron, and first diffraction limited storage ring. The BioMAX beamline is available for macromolecular crystallography, with a second microfocus beamline (MicroMAX) recently funded. There are also beamlines for imaging and, very relevant to CM1306 members, a femtosecond time-resolved instrument.

ESS

The under-construction European Spallation Source will become one of the world’s top sites for neutron structural science when it is completed. Planned instruments relevant for CM1306 include neutron crystallography.

ILL

Co-located with the ESRF on the European Photon and Neutron Campus in Grenoble, the ILL is a research neutron source that operates a range of instruments relevant to structural molecular biology. These include diffraction, scattering and spectroscopy. It also operates a deuteration laboratory.

FRM-II

Research neutron source near Munich, Germany. It operates a beamline for neutron crystallography, as well as a number of other beamlines for spectroscopy and scattering.

Computation and Simulation Infrastructure

Westlife

this is a virtual research environment for structral biology that provides services for computation and data management to researchers in structural biology, integrating multiple approaches and experimental techniques

CCPBioSim

This is a UK-funded collaborative project for biomolecular simulation.

CCP4

This is a UK funded project for macromolecular crystallography that provides open-source software world-wide for academic use as well as training and workshops

CCP-EM

This is a UK funded project for biological electron microscopy. It provides training and support for EM users, as well as maintaining and developing software for biological EM.

CCPN

This is a UK funded project for biological NMR. It provides software and training in NMR data analysis

WeNMR

This is a worldwide e-Infrastructure for NMR and structural biology

MD.USE

Molecular simulation spin-off company from the University of Santiago de Compostela, funded by CM1306 member Rebeca García Fandiño.

PRACE (Partnership for Advanced Computing in Europe)

The mission of PRACE (Partnership for Advanced Computing in Europe) is to enable high-impact scientific discovery and engineering research and development across all disciplines to enhance European competitiveness for the benefit of society. PRACE seeks to realise this mission by offering world class computing and data management resources and services througha peer review process. PRACE also seeks to strengthen the European users of HPC in industry through various initiatives. PRACE has a strong interest in improving energy efficiency of computing systems and reducing their environmental impact.

HPC Europe

HPC Europe is a Pan-European project is based on a program of visit, in the form of traditional transnational access, with researchers visiting HPC centres and/or scientific hosts who will mentor them scientifically and technically for the best exploitation of the HPC resources in their research. The visitors will be funded for travel, accommodation and subsistence, and provided with an amount of computing time suitable for the approved project.


Local Lab-based resources and infrastructure of CM1306 members

Pearson Group

Tailored photocage compounds, sample delivery mounts for serial crystallography experiments.

Mezzetti Group

Facilities for time-resolved FTIR, including step-scan.