Structural biology has seen tremendous progress in the elucidation of static atomic structures of increasingly complex biomolecular systems, many of which are potential targets for future molecular medicine and biotechnology applications. However, understanding of biomolecular mechanism and function also requires knowledge of dynamics, both locally at active sites and more globally in terms of long range domain movements. These dynamic aspects are fundamentally important but difficult to study, often requiring both spectroscopic and structural complementary approaches and methods. Recent advances in the development of such methods make it timely to establish an EU network to bring together the spectroscopic and structural biology communities that will enable integration of the static and dynamic aspects of important biomolecules.
This COST Action will promote the collaborations necessary to achieve this integration, and will disseminate knowledge and target research that will ultimately translate into new understanding of complex biochemical processes. Such knowledge will foster insights into disease states and lead to new biotechnology and future drug discoveries. It will consolidate and further enhance the world-leading role of European groups in these areas and provide a platform for training and promoting ESRs, through a tailored program of Summer Schools, Workshops, Short-Term Scientific Missions, and conferences.
Zagreb, 21-24 March 2018, Croatia – 4th International Scientific Meeting and 5th MC Meeting of COST Action CM1306 – Understanding Movement and Mechanism in Molecular Machines (Registrations open – visit event’s page)
7-9 February 2018, Parma, Italy – COST Training School: Advanced fluorescence methods to explore dynamics and mechanisms of molecular machines – UPDATED PROGRAM
(please submit your application at least two weaks prior to your planned STSM)